MOL2 File Extension

What is MOL2 file?

MOL2 filename suffix is mostly used for Portable Representation Of A SYBYL Molecule files. Portable Representation Of A SYBYL Molecule format was developed by Tripos, L.P.. Files with MOL2 extension may be used by programs distributed for Windows platform. MOL2 file belongs to the Misc Files category just like 6033 other filename extensions listed in our database. The most popular software that supports MOL2 files is Sybyl. Sybyl software was developed by Tripos, L.P., and on its official website you may find more information about MOL2 files or the Sybyl software program.

Programs which support MOL2 file extension

Below is a table that list programs that support MOL2 files. Files with MOL2 suffix can be copied to any mobile device or system platform, but it may not be possible to open them properly on target system.

How to open file with MOL2 extension?

Being unable to open files with MOL2 extension can be have various origins. On the bright side, the most encountered issues pertaining to Portable Representation Of A SYBYL Molecule files aren’t complex. In most cases they can be addressed swiftly and effectively without assistance from a specialist. The list below will guide you through the process of addressing the encountered problem.

Step 1. Get the Sybyl

The most common reason for such problems is the lack of proper applications that supports MOL2 files installed on the system. To address this issue, go to the Sybyl developer website, download the tool, and install it. It is that easy On the top of the page a list that contains all programs grouped based on operating systems supported can be found. If you want to download Sybyl installer in the most secured manner, we suggest you visit Tripos, L.P. website and download from their official repositories.

Step 2. Verify the you have the latest version of Sybyl

You still cannot access MOL2 files although Sybyl is installed on your system? Make sure that the software is up to date. It may also happen that software creators by updating their applications add compatibility with other, newer file formats. If you have an older version of Sybyl installed, it may not support MOL2 format. The latest version of Sybyl should support all file formats that where compatible with older versions of the software.

Step 3. Associate Portable Representation Of A SYBYL Molecule files with Sybyl

If the issue has not been solved in the previous step, you should associate MOL2 files with latest version of Sybyl you have installed on your device. The method is quite simple and varies little across operating systems.

Change the default application in Windows

• Right-click the MOL2 file and choose Open with option
• Click Choose another app and then select More apps option
• Finally select Look for another app on this PC, point to the folder where Sybyl is installed, check the Always use this app to open MOL2 files box and conform your selection by clicking OK button

Change the default application in Mac OS

• By clicking right mouse button on the selected MOL2 file open the file menu and choose Information
• Open the Open with section by clicking its name
• Select the appropriate software and save your settings by clicking Change all
• If you followed the previous steps a message should appear: This change will be applied to all files with MOL2 extension. Next, click the Continue button to finalize the process.

Step 4. Verify that the MOL2 is not faulty

You closely followed the steps listed in points 1-3, but the problem is still present? You should check whether the file is a proper MOL2 file. It is probable that the file is corrupted and thus cannot be accessed.

1. The MOL2 may be infected with malware – make sure to scan it with an antivirus tool.

If the file is infected, the malware that resides in the MOL2 file hinders attempts to open it. It is advised to scan the system for viruses and malware as soon as possible or use an online antivirus scanner. MOL2 file is infected with malware? Follow the steps suggested by your antivirus software.

2. Verify that the MOL2 file’s structure is intact

If you obtained the problematic MOL2 file from a third party, ask them to supply you with another copy. The file might have been copied erroneously and the data lost integrity, which precludes from accessing the file. When downloading the file with MOL2 extension from the internet an error may occurred resulting in incomplete file. Try downloading the file again.

3. Verify whether your account has administrative rights

Some files require elevated access rights to open them. Switch to an account that has required privileges and try opening the Portable Representation Of A SYBYL Molecule file again.

4. Verify that your device fulfills the requirements to be able to open Sybyl

If the system is under havy load, it may not be able to handle the program that you use to open files with MOL2 extension. In this case close the other applications.

5. Ensure that you have the latest drivers and system updates and patches installed

Regularly updated system, drivers, and programs keep your computer secure. This may also prevent problems with Portable Representation Of A SYBYL Molecule files. It may be the case that the MOL2 files work properly with updated software that addresses some system bugs.

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